Perhaps the single greatest barrier to curbing the spread of HIV/AIDS is the dormant, or “latent,” reservoir of virus, which is out of reach of even the most potent medications. But now, scientists at the Gladstone Institutes have uncovered new clues that may help researchers awaken HIV from its slumber—laying the foundation for purging all trace of the virus, and for one day finding a cure for the more than 34 million people worldwide living with HIV/AIDS.
A team of researchers has found a way to map an enzyme’s underlying molecular machinery, revealing patterns that could allow them to predict how an enzyme behaves—and what happens when this process disrupted.
Scientists at the Gladstone Institutes have mapped the molecular mechanism by which a virus known as cytomegalovirus (CMV) so successfully infects its hosts. This discovery paves the way for new research avenues aimed at fighting this and other seemingly benign viruses that can turn deadly.
Scientists at the Gladstone Institutes have identified a novel mechanism by which a type of low-carb, low-calorie diet—called a “ketogenic diet”—could delay the effects of aging.
Scientists at the Gladstone Institutes have mapped the precise frequency by which genes get turned on across the human genome, providing new insight into the most fundamental of cellular processes—and revealing new clues as to what happens when this process goes awry.
New research from an international team of HIV/AIDS experts has reaffirmed the effectiveness of Truvada—the first and only medication approved by the FDA for HIV prevention—expanding our understanding of Truvada’s potency and opening the door to new dosing strategies.
Scientists at the Gladstone Institutes have gotten us one step closer to understanding and overcoming one of the least-understood mechanisms of HIV infection—by devising a method to precisely track the life cycle of individual cells infected with HIV, the virus that causes AIDS.
Warner C. Greene, MD, who directs virology and immunology research at the Gladstone Institutes, has joined with other global AIDS experts to release a locally affordable version of the world’s leading AIDS medical textbook.
Warner C. Greene, MD, PhD, who directs virology and immunology research at the Gladstone Institutes, has been inducted as president of the Association of American Physicians (AAP).