Publications

JJ Miranda, PhDHoldorf MM, Cooper SB, Yamamoto KR, Miranda JJ. Occupancy of chromatin organizers in the Epstein-Barr virus genome. Virology. 2011 Jun 20; 415(1):1-5. View in: PubMed
Ken Nakamura, MD, PhDHertz NT, Berthet A, Sos ML, Thorn KS, Burlingame AL, Nakamura K, Shokat KM. (2013) A neo-substrate that amplifies catalytic activity of Parkinson's disease related kinase PINK1. Cell. 154 (737-747). View in: PubMed
Ken Nakamura, MD, PhDBerthet A, Margolis EB, Zhang J, Hsieh I, Zhang J, Hnasko T, Ahmad J, Edwards RH, Sesaki H, Huang EJ, Nakamura K. (2014) Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J Neuroscience. 34(43):14304-14317 View in: PubMed
Melanie Ott, MD, PhDHerker E, Ott M. Unique ties between hepatitis C virus replication and intracellular lipids. Trends Endocrinol Metab. 2011 Jun;22(6):241-8. Epub 2011 Apr 15. View in: PubMed
Melanie Ott, MD, PhDHerker E, Ott M. Emerging role of lipid droplets in host/pathogen interactions. J Biol Chem. 2012 Jan 20;287(4):2280-7. Epub 2011 Nov 16. View in: PubMed
Melanie Ott, MD, PhDSakane N, Kwon HS, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, Lassen KG, Chan J, Greene WC, Schnoelzer M, Ott M. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog. 2011 Aug;7(8):e1002184. Epub 2011 Aug 18. View in: PubMed
Melanie Ott, MD, PhDHarris C, Herker E, Farese RV Jr, Ott M. Hepatitis C virus core protein decreases lipid droplet turnover: a mechanism for core-induced steatosis. J Biol Chem. 2011 Dec 9;286(49):42615-25. Epub 2011 Oct 7. View in: PubMed
Melanie Ott, MD, PhDHerker E, Harris C, Hernandez C, Carpentier A, Kaehlcke K, Rosenberg AR, Farese RV Jr, Ott M. Efficient hepatitis C virus particle formation requires diacylglycerol acyltransferase-1. Nat Med. 2010 Nov;16(11):1295-8. Epub 2010 Oct 10. View in: PubMed
Jorge J. Palop, PhDPalop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, Yu GQ, Mucke L. Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. J Neurosci. 2005 Oct 19;25(42):9686-93. View in: PubMed
Jorge J. Palop, PhDVerret L, Mann EO, Hang GB, Barth AM, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ. Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell. 2012 Apr 27;149(3):708-21. View in: PubMed