Roddenberry Center for Stem Cell Biology and Medicine
Gladstone founded the Roddenberry Center for Stem Cell Biology and Medicine in 2011 with an unprecedented $5M gift from the Roddenberry Foundation. Deepak Srivastava, MD, leads the Center, which was set up to honor Star Trek creator Gene Roddenberry. In part, the Center builds on pioneering work done by Gladstone Senior Investigator Shinya Yamanaka, MD, PhD—who currently divides his time between Gladstone and Kyoto University’s Center for iPS Cell Research and Application (CiRA). Dr. Yamanaka’s 2006 discovery of induced pluripotent stem cells, or iPS cells, has altered the fields of cell biology and stem cell research—opening promising new prospects for both personalized and regenerative medicine. The Center, which collaborates with CiRA, is creating human, iPS-based disease models needed to accelerate drug development for a host of devastating for cardiovascular, viral and neurological illnesses.
Scientists working at the Center focus on applying the pioneering the principles of stem cell biology for the advancement of human health. The Center provides them with resources for both blue-sky and de-risking work: blue-sky research follows up on promising but uncertain scientific leads; while de-risking research is necessary to move a promising biomedical discovery through all the rigorous tests required for clinical applications.