Center for HIV & Aging at Gladstone
Gladstone investigators, who are at the forefront of tackling this unaddressed issue, have created a preeminent Center with two central imperatives:
- To determine exactly how HIV promotes accelerated aging and what can be done to arrest the process;
- To improve the quality of life for people with HIV by delaying the onset of, and ultimately preventing, these age-related illnesses.
As with all of our research on HIV/AIDS, the investigations at the Center for HIV & Aging are part of Gladstone's broader goals: to better prevent and treat—and ultimately cure—HIV/AIDS.
Our scientists are currently investigating a variety of hypotheses concerning the cause of accelerated aging. Chronic inflammation, itself caused by persistent low-level production of the virus, may be to blame. HIV medications themselves may also be a culprit—or a combination of these factors may be responsible.
Our researchers are uniquely positioned to unravel—and solve—this problem because of our combined expertise in HIV/AIDS biology, aging, chronic inflammation and cancer. Our team of innovative researchers is engaging multiple biological strategies to uncover solutions to this problem.
This research holds the promise of restoring a longer lifespan for people with HIV. It also offers new and important insights into the aging process for those who do not carry the virus.
The Center’s lead investigators include: