Gladstone in the News
The Gladstone Institutes is gratified to receive media attention from around the globe. Check out the highlights of recent press coverage of Gladstone scientists and research. For other news, please be sure to follow us on Facebook and Twitter.
A set of breakthrough studies from U.S. scientists reveals for the first time the fundamental biological mechanism whereby HIV unravels the body’s defenses and causes AIDS, setting the stage for a new generation of sophisticated interventions and preventative treatments.
In a last-ditch effort to rid the body of HIV, droves of white bloods cells self-destruct in an explosive mass suicide that drives the progression toward AIDS, a pair of new studies has found.
The difference between HIV infection and full-blown AIDS is, in large part, the massive die-off of the immune system’s CD4 T-cells. But researchers have only observed the virus killing a small portion of those cells, leading to a longstanding question: What makes the other cells disappear? New research shows that the body is killing its own cells in a little-known process. What’s more, an existing, safe drug could interrupt that self-destruction, thereby offering a way to treat AIDS.
Warner Greene from the Gladstone Institute of Virology and Immunology has been trying to solve the mystery of HIV inffection for years, and he thinks he has finally cracked it. In two papers, published simultaneously in Science and Nature, his team lays out why HIV kills so many bystander cells and, better still, a possible way of stopping it.
Scientists say they have discovered a key process by which the AIDS virus kills key immune cells: It triggers a preprogrammed self-destruct sequence within the cell that is intended to alert fellow immune cells of a crisis.
An anti-inflammatory drug shelved by Vertex Pharmaceuticals Inc. after a mid-stage study in epilepsy patients could be the next big HIV treatment.
The HIV prevention drug Truvada does not increase risky sexual behaviour, scientists have confirmed.
Should people in danger of contracting HIV because they have risky sex take a pill to prevent infection, or will the medication encourage them to take even more sexual risks? After years of debate on this question, a new international study suggests the medication doesn't lead people to stop using condoms or have more sex with more people.
Taking a pill as a preventive measure against HIV infection may not encourage people at high risk for the disease to engage in risky sexual behavior, according to a new U.S. study meant to address fears about its use.
In July 2012, the Food and Drug Administration (FDA) approved Truvada, the first and only drug intended to prevent HIV infection. Now, a new study provides more proof that regular use of Truvada (emtricitabine and tenofovir disoproxil fumarate) can reduce an individual’s risk of contracting HIV by more than 90 percent. Importantly, the researchers also found that use of the pill does not equate to an increase in risky sexual behavior.